CBD CLINICAL RESEARCH HIGHLIGHTS AND FINDINGS
Cannabidiol (CBD) is a widely researched and studied cannabinoid. Here are some highlights of research findings, studies and antidotal reports of benefits. References are included below.
CBD has an anti-depressant effect by its ability to activate serotonin receptors.
CBD has been shown to help in the mediation of body temperature, inflammation and pain by binding to the TRPV-1 receptor.
CBD helps in the preservation of anandamide, a natural cannabinoid of the human body. It does this by suppressing the enzyme responsible for breaking it down, called fatty acid amide hydroxylase. This results in enhancing the body’s own endocannabinoid system by enabling greater activations of the CB1 receptor by anandamide.
CBD counters the psychoactive effects of THC by opposing the action of THC at the CB1 receptor helping mute the effects.
CBD has been shown to demonstrate anti-tumor activity by down regulating and turning off the over-expression at the mRNA and protein level of the 1D-1 gene, found in some aggressive cancers such as leukemia, pancreatic, ovarian, lung, brain and breast cancer.
CBD in combination with THC and other minor cannabinoids is used in the treatment of spasticity (muscle stiffness/spasm) due to multiple sclerosis (MS) in an approved pharmaceutical medication available in dozens of countries.
The list of conditions with published research, clinical trials underway or completed and antidotal reported benefits derived from CBD is extensive including: Acne, ADD/ADHD, Addiction, AIDS, ALS, Alzheimer’s, Anorexia, Antibiotic Resistance, Anxiety, Atherosclerosis, Arthritis, Asthma, Autism, Bipolar, Cancer, Colitis/ Crohn’s, Depression, Diabetes, Endocrine Disorders, Epilepsy/ Seizure, Fibromyalgia, Glaucoma, Heart Disease, Huntington’s, Inflammation, Irritable Bowel, Kidney Disease, Metabolic Syndrome, Migraine, Mood Disorders, Motion Sickness, Multiple Sclerosis, Nausea, Neurodegeneration, Neuropathic Pain, Obesity, OCD, Osteoporosis, Parkinson’s, Prion/ Mad Cow Disease, PTSD, Rheumatism, Schizophrenia, Sickle Cell Anemia, Skin Conditions, Sleep Disorders, Spinal Cord Injury, Stress, Stroke/ TBI
Cannabidiol Counteracts the Psychotropic Side-Effects of Δ-9-Tetrahydrocannabinol in the Ventral Hippocampus through Bidirectional Control of ERK1–2 Phosphorylation | Journal of Neuroscience (jneurosci.org)